TargetMol

Isorhamnetin-3-O-glucoside

Product Code:
 
TAR-T5S1988
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5S1988-1mg1mg£128.00
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TAR-T5S1988-5mg5mg£269.00
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TAR-T5S1988-1mL1 mL * 10 mM (in DMSO)£278.00
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TAR-T5S1988-10mg10mg£402.00
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TAR-T5S1988-25mg25mg£736.00
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TAR-T5S1988-50mg50mg£970.00
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Further Information

Bioactivity:
Isorhamnetin-3-O-glucoside inhibits the activity of alpha-glucosidase from rat intestine; it exhibits a potent rat lens aldose reductase (RLAR) inhibition in vitro, its IC(50) being 1.4 microM and has inhibitory effects of sorbitol accumulation, suggests that it is a leading compound for further study as a new drug for the prevention and/or treatment of diabetes and its complications.
CAS:
5041-82-7
Formula:
C22H22O12
Molecular Weight:
478.406
Purity:
0.9981
SMILES:
COc1cc(ccc1O)-c1oc2cc(O)cc(O)c2c(=O)c1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

References

Antioxidant constituents in the dayflower (Commelina communis L.) and their alpha-glucosidase-inhibitory activity. J Nat Med. 2008 Jul;62(3):349-53. A review of chemistry and biological activities of the genus Aerva--a desert plant. Acta Pol Pharm. 2012 Mar-Apr;69(2):171-7. Inhibitory effects of isorhamnetin-3-O-beta-D-glucoside from Salicornia herbacea on rat lens aldose reductase and sorbitol accumulation in streptozotocin-induced diabetic rat tissues. Biol Pharm Bull. 2005 May;28(5):916-8.