TargetMol

CFT7455

Product Code:
 
TAR-T60024
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T60024-1mg1mg£177.00
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TAR-T60024-5mg5mg£334.00
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TAR-T60024-1mL1 mL * 10 mM (in DMSO)£343.00
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TAR-T60024-10mg10mg£503.00
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TAR-T60024-25mg25mg£768.00
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TAR-T60024-50mg50mg£1,018.00
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This product comes from: United States.
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Further Information

Bioactivity:
CFT7455 is an anti-cancer agent showing high affinity to the cereblon E3 ligase with a Kd of 0.9 nM. CFT7455 is an orally active degrader of zinc finger transcription factors Ikaros (IKZF1), and Aiolos (IKZF3).
CAS:
2504235-67-8
Formula:
C28H27N3O4
Molecular Weight:
469.53
Pathway:
PROTAC
Purity:
0.9794
SMILES:
O=C1C2=C3C(C(CC4=CC=C(CN5CCOCC5)C=C4)=CC=C3N1[C@@H](CCC6=O)C(N6)=O)=CC=C2
Target:
Ligand for E3 Ligase

References

David Proia, et al. Advantageous therapies for disorders mediated by ikaros or aiolos. WO2022032132A1.