TargetMol

TDI-011536

Product Code:
 
TAR-T60144
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T60144-5mg5mg£111.00
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TAR-T60144-10mg10mg£135.00
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TAR-T60144-25mg25mg£209.00
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TAR-T60144-50mg50mg£294.00
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Quantity:
TAR-T60144-100mg100mg£436.00
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Quantity:
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Further Information

Bioactivity:
TDI-011536 is a potent Lats kinase inhibitor. TDI-011536 interrupts Hippo-Yap signaling and initiates the proliferation of lesioned heartmuscle cells. TDI-011536 can be used in studies of organ conservation and regeneration.
CAS:
2687970-96-1
Formula:
C19H16N4O2S
Molecular Weight:
364.42
Purity:
0.98
SMILES:
C(N1C(=NC(=O)C=2C=3C(NC2)=NC=CC3)SC=C1CO)C4=CC=CC=C4

References

Kastan NR, et al. Development of an improved inhibitor of Lats kinases to promote regeneration of mammalian organs. Proc Natl Acad Sci U S A. 2022 Jul 12;119(28):e2206113119.