TargetMol

CORM-3

Product Code:
 
TAR-T6454
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6454-5mg5mg£109.00
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Quantity:
TAR-T6454-10mg10mg£133.00
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TAR-T6454-25mg25mg£173.00
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TAR-T6454-50mg50mg£224.00
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Quantity:
TAR-T6454-100mg100mg£300.00
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This product comes from: United States.
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Further Information

Bioactivity:
CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity.
CAS:
475473-26-8
Formula:
C5H4ClNO5Ru
Molecular Weight:
294.61
Pathway:
Immunology/Inflammation; ; NF-κb
Purity:
0.98
SMILES:
[C-]#[O+].[C-]#[O+].[C-]#[O+].NCC(=O)O[Ru]Cl
Target:
NF-κB; NOD-like Receptor (NLR)

References

Tian X, Liu X, Wang A, et al. Bioluminescence Imaging of Carbon Monoxide in Living Cells and Nude Mice Based on Pd0-Mediated Tsuji?Trost Reaction. Analytical chemistry. 2018 May 1;90(9):5951-5958. Ferr?ndiz ML, et al. Ann Rheum Dis. 2008 Sep;67(9):1211-7. Huang Y, et al. Carbon monoxide (CO) inhibits hydrogen peroxide (H2O2)-induced oxidative stress and the activation of NF-?B signaling in lens epithelial cells. Exp Eye Res. 2018 Jan;166:29-39. Long R, et al. Biochim Biophys Acta. 2014, 1837(1), 201-209. Clark JE, et al. Circ Res. 2003, 93(2), e2-8. Sawle P, et al. Br J Pharmacol. 2005, 145(6), 800-810. Tian X, Liu X, Wang A, et al. Bioluminescence Imaging of Carbon Monoxide in Living Cells and Nude Mice Based on Pd0-Mediated Tsuji?Trost Reaction[J]. Analytical chemistry. 2018 May 1;90(9):5951-5958.