TargetMol

Encorafenib

Product Code:
 
TAR-T6487
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6487-1mg1mg£108.00
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TAR-T6487-5mg5mg£140.00
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TAR-T6487-10mg10mg£170.00
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TAR-T6487-25mg25mg£229.00
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TAR-T6487-50mg50mg£371.00
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This product comes from: United States.
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Further Information

Bioactivity:
LGX818 is an orally available mutated BRaf V600E inhibitor(IC50=0.3 nM) with potential antineoplastic activity.
CAS:
1269440-17-6
Formula:
C22H27ClFN7O4S
Molecular Weight:
540.01
Pathway:
MAPK
Purity:
0.9974
SMILES:
COC(=O)N[C@@H](C)CNc1nccc(n1)-c1cn(nc1-c1cc(Cl)cc(NS(C)(=O)=O)c1F)C(C)C
Target:
Raf

References

Darrin D Stuart, et al. Cancer Res, 2012, 72(8 Supplement): 3790 Li B, Ming H, Qin S, et al.HSPA8 Activates Wnt/??Catenin Signaling to Facilitate BRAF V600E Colorectal Cancer Progression by CMA?Mediated CAV1 Degradation.Advanced Science.2023: 2306535.