TargetMol

Elaiophylin

Product Code:
 
TAR-T6769
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6769-1mg1mg£204.00
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TAR-T6769-5mg5mg£463.00
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TAR-T6769-1mL1 mL * 10 mM (in DMSO)£503.00
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This product comes from: United States.
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Further Information

Bioactivity:
Elaiophylin shows antiprotozoal activity against Plasmodium falciparum K1a and Trypanosoma brucei brucei GUTat 3.1 strains with IC50 of 0.36 μM and 0.45 μM, respectively.
CAS:
37318-06-2
Formula:
C54H88O18
Molecular Weight:
1025.27
Pathway:
; Autophagy
Purity:
0.98
SMILES:
CC[C@H]1[C@@H](C[C@](O[C@@H]1C)(O)[C@H]([C@H](O)[C@@H]([C@H]2OC(=O)/C=C/C=C/[C@@H]([C@H](OC(=O)/C=C/C=C/[C@@H]2C)[C@H]([C@@H](O)[C@@H]([C@@]3(O[C@@H]([C@H]([C@@H](C3)O[C@@H]4O[C@H]([C@H]([C@H](C4)O)O)C)CC)C)O)C)C)C)C)C)O[C@@H]5O[C@H]([C@H]([C@H](C5)O)O)C
Target:
Autophagy

References

Otoguro K, et al. J Antibiot (Tokyo). 2010, 63(5), 275-277. Liu CM, et al. J Antibiot (Tokyo). 1993, 46(2), 350-352. Zhao X, et al Elaiophylin, a novel autophagy inhibitor, exerts antitumor activity as a single agent in ovarian cancer cells. Autophagy. 2015;11(10):1849-63. Dr?se S, et al. Biochemistry. 1993, 32(15), 3902-3906. Ritzau M, et al. J Nat Prod. 1998, 61(11), 1337-1339. Hammann P, et al. J Antibiot (Tokyo). 1990, 43(11), 1431-1440.