TargetMol

Motolimod

Product Code:
 
TAR-T6898
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6898-1mg1mg£111.00
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TAR-T6898-2mg2mg£129.00
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TAR-T6898-5mg5mg£168.00
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TAR-T6898-1mL1 mL * 10 mM (in DMSO)£179.00
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TAR-T6898-10mg10mg£229.00
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TAR-T6898-25mg25mg£389.00
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TAR-T6898-50mg50mg£546.00
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TAR-T6898-100mg100mg£749.00
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This product comes from: United States.
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Further Information

Bioactivity:
Motolimod (VTX-2337) is an effective and specific Toll-like receptor (TLR) 8 agonist (EC50: 100 nM), > 50-fold selectivity over TLR7.
CAS:
926927-61-9
Formula:
C28H34N4O2
Molecular Weight:
458.606
Pathway:
Immunology/Inflammation
Purity:
0.9927
SMILES:
CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)-c1ccc(cc1)C(=O)N1CCCC1
Target:
TLR

References

Yang W, Sun X, Liu S, et al.TLR8 agonist Motolimod-induced inflammatory death for treatment of acute myeloid leukemia.Biomedicine & Pharmacotherapy.2023, 163: 114759. Monk BJ, et al. J Clin Oncol 31, 2013 (suppl; abstr 3077). Lu H, et al. Clin Cancer Res. 2012, 18(2), 499-509.