TargetMol

SB 239063

Product Code:
 
TAR-T6976
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6976-1mg1mg£105.00
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TAR-T6976-2mg2mg£117.00
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TAR-T6976-1mL1 mL * 10 mM (in DMSO)£128.00
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TAR-T6976-5mg5mg£142.00
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TAR-T6976-10mg10mg£201.00
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TAR-T6976-25mg25mg£354.00
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TAR-T6976-50mg50mg£495.00
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TAR-T6976-100mg100mg£687.00
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This product comes from: United States.
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Further Information

Bioactivity:
SB239063 is a potent and selective p38 MAPKα/β inhibitor with IC50 of 44 nM, showing no activity against the γ- and δ-kinase isoforms.
CAS:
193551-21-2
Formula:
C20H21FN4O2
Molecular Weight:
368.412
Pathway:
MAPK; Autophagy
Purity:
0.9981
SMILES:
COc1nccc(n1)-c1c(ncn1[C@H]1CC[C@H](O)CC1)-c1ccc(F)cc1
Target:
p38 MAPK; Autophagy

References

Strassburger M, et al. Eur J Pharmacol. 2008, 592(1-3), 55-61. Joko T, et al. Exp Eye Res. 2013, 108, 23-32. Underwood DC, et al. J Pharmacol Exp Ther. 2000, 293(1), 281-288. Li F, et al. Eur Respir J. 2011, 37(4), 933-942.