TargetMol

Z-IETD-FMK

Product Code:
 
TAR-T7019
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7019-1mg1mg£173.00
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Quantity:
TAR-T7019-2mg2mg£224.00
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TAR-T7019-5mg5mg£292.00
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TAR-T7019-1mL1 mL * 10 mM (in DMSO)£417.00
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TAR-T7019-10mg10mg£430.00
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Quantity:
TAR-T7019-25mg25mg£664.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Z-IETD-FMK is a selective caspase 8 inhibitor, which has cell permeable.
CAS:
210344-98-2
Formula:
C30H43FN4O11
Molecular Weight:
654.689
Pathway:
Apoptosis; Proteases/Proteasome
Purity:
0.9981
SMILES:
CC[C@H](C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CCC(=O)OC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)OC)C(=O)CF
Target:
Caspase

References

Silva EM, et al. J Immunol. 2005, 174(10), 6314-6321. Liu X, Song X, Luan D, et al. Real-time in situ Visualizing the Sequential Activation of Caspase Cascade Using a Multi-color Au-Se Bonding Fluorescent Nanoprobe. Analytical Chemistry. 2019, 91(9): 5994-6002 Wang J, et al. J Card Fail. 2000, 6(3), 243-249. Tezel G, et al. Invest Ophthalmol Vis Sci. 1999, 40(11), 2660-2667. Monnier PP, et al. J Neurosci. 2011, 31(29), 10494-10505. Liu X, Song X, Luan D, et al. Real-time in situ Visualizing the Sequential Activation of Caspase Cascade Using a Multi-color Au-Se Bonding Fluorescent Nanoprobe[J]. Analytical chemistry. 2019 May 7;91(9):5994-6002. Hussain M, Lu Y, Tariq M, et al. A small-molecule Skp1 inhibitor elicits cell death by p53-dependent mechanism. Iscience. 2022, 25(7): 104591.