TargetMol

Dronedarone

Product Code:
 
TAR-T7056
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7056-10mg10mg£109.00
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Quantity:
TAR-T7056-1mL1 mL * 10 mM (in DMSO)£113.00
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TAR-T7056-50mg50mg£194.00
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This product comes from: United States.
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Further Information

Bioactivity:
Dronedarone is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.
CAS:
141626-36-0
Formula:
C31H44N2O5S
Molecular Weight:
556.76
Pathway:
Membrane transporter/Ion channel; Neuroscience; Autophagy; Metabolism; GPCR/G Protein
Purity:
0.9955
SMILES:
CCCCN(CCCC)CCCOc1ccc(cc1)C(=O)c1c(CCCC)oc2ccc(NS(C)(=O)=O)cc12
Target:
P45; Potassium Channel; Calcium Channel; Sodium Channel; Adrenergic Receptor; AChR; Autophagy

References

Altomare C, et al. Effects of dronedarone on Acetylcholine-activated current in rabbit SAN cells[J]. British Journal of Pharmacology, 2010, 130(6):1315-1320. Aimond F, et al. Cellular and in vivo electrophysiological effects of dronedarone in normal and postmyocardial infarcted rats.[J]. Journal of Pharmacology & Experimental Therapeutics, 2000, 292(1):415. Varr? A, et al. Electrophysiological effects of dronedarone (SR 33589), a noniodinated amiodarone derivative in the canine heart: comparison with amiodarone.[J]. Br J Pharmacol, 2010, 133(5):625-634. Bogdan R, et al. Effect of dronedarone on Na+, Ca2+ and HCN channels[J]. Naunyn-Schmiedeberg's Archives of Pharmacology, 2011, 383(4):347-356.