TargetMol

S29434

Product Code:
 
TAR-T7149
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7149-1mg1mg£111.00
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TAR-T7149-5mg5mg£168.00
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TAR-T7149-1mL1 mL * 10 mM (in DMSO)£177.00
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TAR-T7149-10mg10mg£229.00
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TAR-T7149-25mg25mg£389.00
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TAR-T7149-50mg50mg£544.00
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Further Information

Bioactivity:
S29434 (NMDPEF) is a potent, competitiveinhibitor of quinone reductase 2 (QR2;IC50:5-16nM).
CAS:
874484-20-5
Formula:
C21H18N4O3
Molecular Weight:
374.4
Pathway:
Metabolism; Autophagy
Purity:
0.9992
SMILES:
COc1ccc2n3Cc4cccnc4-c3c(CCNC(=O)c3ccco3)c2n1
Target:
NADPH; Autophagy

References

Laure-Estelle C , Nambinina R , Serena S , et al. Role of Quinone Reductase 2 in the Antimalarial Properties of Indolone-Type Derivatives[J]. Molecules, 2017, 22(2):210-. Boutin JA, Bouillaud F, Janda E,et al.S29434, a Quinone Reductase 2 Inhibitor: Main Biochemical and Cellular Characterization[J].Mol Pharmacol. 2019 Mar;95(3):269-285.