TargetMol

DAPTA

Product Code:
 
TAR-T7624
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7624-1mg1mg£108.00
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TAR-T7624-5mg5mg£142.00
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TAR-T7624-10mg10mg£195.00
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TAR-T7624-25mg25mg£309.00
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TAR-T7624-50mg50mg£426.00
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Quantity:
TAR-T7624-100mg100mg£584.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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  • Further Information
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Further Information

Bioactivity:
DAPTA(TFA) is an inhibitor of CCR5, shows potent anti-HIV activities.
CAS:
106362-34-9
Formula:
C35H56N10O15
Molecular Weight:
856.888
Pathway:
Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
Purity:
1
SMILES:
C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](C)N)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O)C(N)=O
Target:
HIV Protease; CCR

References

Michael R. Ruff, Maria Polianova, Quan-en Yang, Gifford S. Leoung, Francis W. Ruscetti, Candace B. Pert. Update on D-Ala-Peptide T-Amide (DAPTA): A Viral Entry Inhibitor that Blocks CCR5 Chemokine Receptors[J]. Current HIV Research, 2003, 1(1):p.51-67. Pollicita M , Ruff M R , Pert C B , et al. Profound Anti-HIV-1 Activity of DAPTA in Monocytes/macrophages and Inhibition of CCR5-mediated Apoptosis in Neuronal Cells[J]. Antiviral Chemistry and Chemotherapy, 2007, 18(5):285-295.