TargetMol

BS194

Product Code:
 
TAR-T7698
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7698-1mg1mg£149.00
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TAR-T7698-2mg2mg£193.00
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TAR-T7698-5mg5mg£254.00
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TAR-T7698-1mL1 mL * 10 mM (in DMSO)£274.00
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TAR-T7698-10mg10mg£346.00
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TAR-T7698-25mg25mg£536.00
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TAR-T7698-50mg50mg£736.00
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TAR-T7698-100mg100mg£994.00
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Further Information

Bioactivity:
BS194 is as a potent cyclin-dependent protein kinases (CDKs) inhibitor.
CAS:
1092443-55-4
Formula:
C20H27N5O3
Molecular Weight:
385.468
Pathway:
Cell Cycle/Checkpoint
Purity:
0.9964
SMILES:
CC(C)c1cnn2c(NCc3ccccc3)cc(N[C@@H](CO)[C@H](O)CO)nc12
Target:
CDK

References

Heathcote D A , Patel H , Kroll S H , et al. A Novel Pyrazolo[1,5-a]pyrimidine Is a Potent Inhibitor of Cyclin-Dependent Protein Kinases 1, 2, and 9, Which Demonstrates Antitumor Effects in Human Tumor Xenografts Following Oral Administration.[J]. Journal of Medicinal Chemistry, 2010, 53(24):8508-8522. Exploring the selectivity of a ligand complex with CDK2/CDK1: a molecular dynamics simulation approach[J]. Journal of Molecular Recognition, 2012, 25(10):504?512.