TargetMol

H3B-6527

Product Code:
 
TAR-T7738
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7738-1mg1mg£136.00
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Quantity:
TAR-T7738-2mg2mg£181.00
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TAR-T7738-5mg5mg£224.00
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TAR-T7738-1mL1 mL * 10 mM (in DMSO)£309.00
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TAR-T7738-10mg10mg£337.00
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Quantity:
TAR-T7738-25mg25mg£519.00
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Quantity:
TAR-T7738-50mg50mg£703.00
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Quantity:
TAR-T7738-100mg100mg£970.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma, with antineoplastic activity.
CAS:
1702259-66-2
Formula:
C29H34Cl2N8O4
Molecular Weight:
629.54
Pathway:
Angiogenesis; Tyrosine Kinase/Adaptors
Purity:
0.9985
SMILES:
CCN1CCN(CC1)c1ccc(Nc2cc(ncn2)N(C)C(=O)Nc2c(Cl)c(OC)cc(OC)c2Cl)c(NC(=O)C=C)c1
Target:
FGFR

References

Zhongwei, Xin, Xuemin, et al. Blocking FGFR4 exerts distinct anti-tumorigenic effects in esophageal squamous cell carcinoma.[J]. Thoracic cancer, 2018. Joshi, Jaya Julie, Coffey, Heather, Corcoran, Erik,et al. H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma[J]. Cancer Research, 77(24):6999-7013.