TargetMol

C25-140

Product Code:
 
TAR-T7889
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T7889-1mg1mg£125.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T7889-1mL1 mL * 10 mM (in DMSO)£189.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T7889-5mg5mg£189.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T7889-10mg10mg£254.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T7889-25mg25mg£442.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T7889-50mg50mg£624.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T7889-100mg100mg£860.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
C25-140 is a small-molecule inhibitor of TRAF6-Ubc13.
CAS:
1358099-18-9
Formula:
C26H31N7O
Molecular Weight:
457.582
Pathway:
Ubiquitination; NF-κb; Apoptosis;
Purity:
1
SMILES:
Cc1nn(c(C)c1CCC(=O)N1CCC(Cc2ccccc2)CC1)-c1ccc2nnc(C)n2n1
Target:
TNF; E1/E2/E3 Enzyme; NF-κB

References

Zhao G, Tong Y, Xu J, et al.Jing-Fang powder ethyl acetate extracts attenuate atopic dermatitis by modulating T-cell activity.Molecular Immunology.2023, 160: 133-149. Kerstin B J , Maria P G , Kenji S , et al. Targeting TRAF6 E3 ligase activity with a small molecule inhibitor combats autoimmunity[J]. Journal of Biological Chemistry, 2018:jbc.RA118.002649-.