TargetMol

VPS34 inhibitor 1 (Compound 19, PIK-III analogue)

Product Code:
 
TAR-T7944
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7944-1mg1mg£149.00
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TAR-T7944-2mg2mg£169.00
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TAR-T7944-5mg5mg£250.00
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TAR-T7944-10mg10mg£346.00
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TAR-T7944-25mg25mg£536.00
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TAR-T7944-50mg50mg£736.00
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TAR-T7944-100mg100mg£994.00
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Further Information

Bioactivity:
VPS34 inhibitor 1 (Compound 19, PIK-III analogue) is a potent and selective inhibitor of VPS34( IC50 : 15 nM)
CAS:
1383716-46-8
Formula:
C21H25N7O
Molecular Weight:
391.479
Pathway:
PI3K/Akt/mTOR signaling
Purity:
0.9844
SMILES:
CC(C)(O)CNc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccncc2)n1
Target:
PI3K

References

Honda A , Harrington E , Cornella-Taracido I , et al. Potent, Selective, and Orally Bioavailable Inhibitors of VPS34 Provide Chemical Tools to Modulate Autophagy in Vivo[J]. ACS Medicinal Chemistry Letters, 2015, 7(1).