TargetMol

L-732138

Product Code:
 
TAR-T8235
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8235-1mg1mg£95.00
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TAR-T8235-2mg2mg£106.00
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TAR-T8235-5mg5mg£128.00
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TAR-T8235-1mL1 mL * 10 mM (in DMSO)£134.00
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TAR-T8235-10mg10mg£168.00
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TAR-T8235-25mg25mg£254.00
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TAR-T8235-50mg50mg£389.00
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TAR-T8235-100mg100mg£544.00
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This product comes from: United States.
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Further Information

Bioactivity:
L-732138 is a potent and competitive antagonist of neurokinin-1 (NK-1) receptor(IC50 : 2.3 nM)
CAS:
148451-96-1
Formula:
C22H18F6N2O3
Molecular Weight:
472.387
Pathway:
Neuroscience; GPCR/G Protein
Purity:
1
SMILES:
CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1cc(cc(c1)C(F)(F)F)C(F)(F)F
Target:
Neurokinin receptor

References

Mu?oz M, et al. The NK-1 Receptor Antagonist L-732,138 Induces Apoptosis and Counteracts Substance P-Related Mitogenesis in Human Melanoma Cell Lines. Cancers (Basel). 2010 Apr 20;2(2):611-23. 2 .Kuo HP, et al. Lipopolysaccharide enhances neurogenic plasma exudation in guinea-pig airways. Br J Pharmacol. 1998 Oct;125(4):711-6.