TargetMol

ZSET1446

Product Code:
 
TAR-T8448
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8448-1mg1mg£135.00
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TAR-T8448-2mg2mg£164.00
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TAR-T8448-5mg5mg£217.00
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TAR-T8448-1mL1 mL * 10 mM (in DMSO)£242.00
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TAR-T8448-10mg10mg£279.00
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TAR-T8448-25mg25mg£490.00
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TAR-T8448-50mg50mg£680.00
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TAR-T8448-100mg100mg£922.00
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This product comes from: United States.
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Further Information

Bioactivity:
ZSET-1446 is a T-type calcium channel activator potentially for the treatment of learning deficits in various types of Alzheimer disease (AD) models.
CAS:
887603-94-3
Formula:
C15H12N2O
Molecular Weight:
236.274
Pathway:
Neuroscience; Metabolism; Membrane transporter/Ion channel
Purity:
0.9932
SMILES:
O=C1N=C2C=CC=CN2C11Cc2ccccc2C1
Target:
Calcium Channel; AChR

References

Yamaguchi Y, et al. Combination effects of ZSET1446/ST101 with memantine on cognitive function and extracellular acetylcholine in the hippocampus. J Pharmacol Sci. 2013;123(4):347-55. Epub 2013 Nov 29. Yamaguchi Y, et al. Effects of ZSET1446/ST101 on cognitive deficits and amyloid ? deposition in the senescence accelerated prone mouse brain. J Pharmacol Sci. 2012;119(2):160-6.