TargetMol

Spastazoline

Product Code:
 
TAR-T8513
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8513-1mg1mg£109.00
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TAR-T8513-5mg5mg£161.00
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TAR-T8513-1mL1 mL * 10 mM (in DMSO)£171.00
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TAR-T8513-10mg10mg£222.00
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TAR-T8513-25mg25mg£374.00
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TAR-T8513-50mg50mg£527.00
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Quantity:
TAR-T8513-100mg100mg£725.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Spastazoline is a potent and selective inhibitor of spastin(Human spastin with IC50 of 99 nM ).
CAS:
2351882-11-4
Formula:
C20H30N8
Molecular Weight:
382.516
Purity:
1
SMILES:
CC(C)[C@@H]1CN(CCN1)c1nc(Nc2cc([nH]n2)C(C)(C)C)c2cc[nH]c2n1

References

Cupido T, et al. Designing a chemical inhibitor for the AAA protein spastin using active site mutations. Nat Chem Biol. 2019 Feb 18. Pisa R , Cupido T , Steinman J B , et al. Analyzing Resistance to Design Selective Chemical Inhibitors for AAA Proteins[J]. Cell Chemical Biology, 2019, 26(9).