TargetMol

BC-1382

Product Code:
 
TAR-T8564
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8564-1mg1mg£144.00
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TAR-T8564-5mg5mg£250.00
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TAR-T8564-1mL1 mL * 10 mM (in DMSO)£285.00
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TAR-T8564-10mg10mg£337.00
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TAR-T8564-25mg25mg£523.00
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TAR-T8564-50mg50mg£723.00
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TAR-T8564-100mg100mg£978.00
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TAR-T8564-500mg500mg£1,886.00
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Further Information

Bioactivity:
BC-1382 is a potent ubiquitin E3 ligase HECTD2 inhibitor that specificly disrupts the HECTD2/PIAS1 interaction(IC50 of 5 nM).
CAS:
1013753-99-5
Formula:
C23H29N3O5S
Molecular Weight:
459.56
Pathway:
Ubiquitination;
Purity:
0.9972
SMILES:
COc1ccccc1CNC(=O)[C@H](C)NC(=O)C1CCN(CC1)S(=O)(=O)c1ccccc1
Target:
E1/E2/E3 Enzyme

References

Coon T A , Mckelvey A C , Lear T , et al. The proinflammatory role of HECTD2 in innate immunity and experimental lung injury[J]. ence Translational Medicine, 2015, 7(295):295ra109.