TargetMol

Elamipretide Triacetate

Product Code:
 
TAR-T8644
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8644-1mg1mg£177.00
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TAR-T8644-2mg2mg£230.00
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TAR-T8644-5mg5mg£309.00
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TAR-T8644-10mg10mg£434.00
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TAR-T8644-25mg25mg£670.00
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TAR-T8644-50mg50mg£914.00
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Quantity:
TAR-T8644-100mg100mg£1,211.00
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This product comes from: United States.
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Further Information

Bioactivity:
Elamipretide TriTFA is an aromatic-cationic tetrapeptide that readily penetrates cell membranes and transiently localizes to the inner mitochondrial membrane where it associates with cardiolipin.It has been used in trials studying the treatment of Leber's Hereditary Optic Neuropathy.
CAS:
1849610-71-4
Formula:
C38H61N9O11
Molecular Weight:
819.958
Purity:
1
SMILES:
CC(O)=O.CC(O)=O.CC(O)=O.Cc1cc(O)cc(C)c1C[C@H](NC(=O)[C@H](N)CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

References

Chatfield K C , Sparagna G C , Chau S , et al. Elamipretide Improves Mitochondrial Function in the Failing Human Heart[J]. JACC: Basic to Translational ence, 2019, 4( 2):147-157. Amel, Karaa, Richard, et al. Randomized dose-escalation trial of elamipretide in adults with primary mitochondrial myopathy.[J]. Neurology, 2018.