TargetMol

HA-1004 dihydrochloride

Product Code:
 
TAR-T8681
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8681-1mg1mg£368.00
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Further Information

Bioactivity:
HA-1004 dihydrochloride is an inhibitor of PKA, PKC, cGKI, MYLK, and calcium channel protein
CAS:
92564-34-6
Formula:
C12H16ClN5O2S
Molecular Weight:
329.8
Pathway:
Cytoskeletal Signaling; Metabolism; Chromatin/Epigenetic; Membrane transporter/Ion channel; Tyrosine Kinase/Adaptors
Purity:
0.98
SMILES:
Cl.NC(N)=NCCNS(=O)(=O)c1cccc2cnccc12
Target:
Calcium Channel; PKA; PKC

References

Ishikawa T , Inagaki M , Watanabe M , et al. Relaxation of vascular smooth muscle by HA-1004, an inhibitor of cyclic nucleotide-dependent protein kinase[J]. Journal of Pharmacology and Experimental Therapeutics, 1985, 235(2):495-499. Maurice G H , Ruey T L , Chipkin S R . The isoquinoline sulfonamide inhibitors of protein phosphorylation, H-7, H-8, and HA-1004, also inhibit RNA synthesis: studies on responses of adipose tissue to growth hormone.[J]. Endocrinology, 1990(1):441.