TargetMol

HBT1

Product Code:
 
TAR-T8779
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8779-5mg5mg£103.00
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TAR-T8779-10mg10mg£124.00
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TAR-T8779-1mL1 mL * 10 mM (in DMSO)£125.00
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TAR-T8779-25mg25mg£177.00
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TAR-T8779-50mg50mg£229.00
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TAR-T8779-100mg100mg£337.00
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Further Information

Bioactivity:
HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons. HBT1 binds to ligand-binding domain of AMPA-R in glutamate dependent manner.
CAS:
489408-02-8
Formula:
C16H17F3N4O2S
Molecular Weight:
386.39
Pathway:
Neuroscience
Purity:
0.9948
SMILES:
Cc1cc(nn1CC(=O)Nc1sc2CCCCc2c1C(N)=O)C(F)(F)F
Target:
GluR

References

Kunugi A , Tajima Y , Kuno H , et al. HBT1, a novel AMPA receptor potentiator with lower agonistic effect, avoided bell-shaped response in in vitro BDNF production[J]. Journal of Pharmacology & Experimental Therapeutics, 2018:jpet.117.245050.