TargetMol

4-MMPB

Product Code:
 
TAR-T8794
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8794-1mg1mg£127.00
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TAR-T8794-5mg5mg£209.00
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TAR-T8794-1mL1 mL * 10 mM (in DMSO)£222.00
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TAR-T8794-10mg10mg£303.00
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TAR-T8794-25mg25mg£503.00
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TAR-T8794-50mg50mg£695.00
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TAR-T8794-100mg100mg£946.00
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Further Information

Bioactivity:
15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM. 4-MMPB has IC50s of 19.5 μM and 19.1 μM for soybean 15-lipoxygenase (SLO) and human 15-lipoxygenase-1 (15-LOX-1), respectively. 4-MMPB has potential for the research of prostate cancer.
CAS:
928853-86-5
Formula:
C16H19N5S
Molecular Weight:
313.42
Pathway:
Metabolism; Apoptosis;
Purity:
0.9875
SMILES:
CN1CCN(CC1)c1nc(C)c2Nc3ccccc3Sc2n1
Target:
Apoptosis; Lipoxygenase

References

Saboormaleki S , Sadeghian H , Bahrami A R , et al. 7-Farnesyloxycoumarin Exerts Anti-cancer Effects on a Prostate Cancer Cell Line by 15-LOX-1 Inhibition[J]. Archives of Iranian Medicine, 2018, 21(6):251-259. Nikpour M , Mousavian M , Mahdieh Davoodnejad?. Synthesis of new series of pyrimido[4,5- b ][1,4] benzothiazines as 15-lipoxygenase inhibitors and study of their inhibitory mechanism[J]. Medicinal Chemistry Research, 2013, 22(10):5036-5043. Alavi S J , Sadeghian H , Seyedi S M , et al. A novel class of human 15-LOX-1 inhibitors based on 3-hydroxycoumarin[J]. Chemical Biology & Drug Design, 2018.