TargetMol

APS6-45

Product Code:
 
TAR-T8843
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8843-1mg1mg£130.00
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TAR-T8843-5mg5mg£213.00
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TAR-T8843-1mL1 mL * 10 mM (in DMSO)£246.00
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TAR-T8843-10mg10mg£303.00
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TAR-T8843-25mg25mg£495.00
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TAR-T8843-50mg50mg£688.00
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Quantity:
TAR-T8843-100mg100mg£938.00
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Further Information

Bioactivity:
APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity.
CAS:
2188236-41-9
Formula:
C23H16F8N4O3
Molecular Weight:
548.393
Pathway:
GPCR/G Protein; MAPK
Purity:
1
SMILES:
CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3cc(ccc3F)C(F)(C(F)(F)F)C(F)(F)F)cc2)ccn1
Target:
MAPK; Ras

References

Sonoshita M, Scopton AP, Ung PMU, et al. A whole-animal platform to advance a clinical kinase inhibitor into new disease space. Nat Chem Biol. 2018;14(3):291-298. doi:10.1038/nchembio.2556