TargetMol

I3MT-3

Product Code:
 
TAR-T8851
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8851-1mg1mg£127.00
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TAR-T8851-5mg5mg£209.00
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TAR-T8851-1mL1 mL * 10 mM (in DMSO)£219.00
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TAR-T8851-10mg10mg£289.00
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TAR-T8851-25mg25mg£510.00
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TAR-T8851-50mg50mg£704.00
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TAR-T8851-100mg100mg£938.00
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TAR-T8851-500mg500mg£1,830.00
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Further Information

Bioactivity:
I3MT-3 (HMPSNE) is a potent, selective and cell membrane permeability inhibitor of 3-mercaptopyruvate sulfur transferase (3MST), which targets the persulfated cysteine residues located at the active site of 3MST.
CAS:
459420-09-8
Formula:
C17H14N2O2S
Molecular Weight:
310.37
Pathway:
Stem Cells
Purity:
0.9986
SMILES:
Cc1cc(O)nc(SCC(=O)c2cccc3ccccc23)n1
Target:
Hippo pathway

References

Hanaoka K, Sasakura K, Suwanai Y, et al. Discovery and Mechanistic Characterization of Selective Inhibitors of H2S-producing Enzyme: 3-Mercaptopyruvate Sulfurtransferase (3MST) Targeting Active-site Cysteine Persulfide. Sci Rep. 2017;7:40227. Published 2017 Jan 12. doi:10.1038/srep40227