TargetMol

653-47 hydrochloride

Product Code:
 
TAR-T8890
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8890-1mg1mg£138.00
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TAR-T8890-5mg5mg£229.00
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TAR-T8890-1mL1 mL * 10 mM (in DMSO)£252.00
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TAR-T8890-10mg10mg£369.00
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TAR-T8890-25mg25mg£576.00
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TAR-T8890-50mg50mg£790.00
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TAR-T8890-100mg100mg£1,050.00
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TAR-T8890-500mg500mg£2,038.00
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This product comes from: United States.
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Further Information

Bioactivity:
653-47 hydrochloride is a potentiator, significantly potentiates the cAMP-response element binding protein (CREB) inhibitory activity of 666-15. It is also a very weak CREB inhibitor with IC50 of 26.3 μM.
CAS:
1224567-46-7
Formula:
C20H20Cl2N2O3
Molecular Weight:
407.29
Pathway:
Chromatin/Epigenetic
Purity:
0.9965
SMILES:
Cl.NCCCOc1cc2ccccc2cc1C(=O)Nc1ccc(Cl)cc1O
Target:
Epigenetic Reader Domain

References

Xie F, et al. Discovery of a Synergistic Inhibitor of cAMP-Response Element Binding Protein (CREB)-Mediated Gene Transcription with 666-15. J Med Chem. 2019;62(24):11423-11429.