TargetMol

GW280264X

Product Code:
 
TAR-T8961
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8961-1mg1mg£205.00
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Quantity:
TAR-T8961-5mg5mg£356.00
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Quantity:
TAR-T8961-1mL1 mL * 10 mM (in DMSO)£431.00
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TAR-T8961-10mg10mg£495.00
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Quantity:
TAR-T8961-25mg25mg£760.00
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Quantity:
TAR-T8961-50mg50mg£1,018.00
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Quantity:
TAR-T8961-100mg100mg£1,348.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
GW280264X is an inhibitor of ADAM17 .
CAS:
866924-39-2
Formula:
C28H41N5O6S
Molecular Weight:
575.73
Pathway:
Proteases/Proteasome
Purity:
0.9951
SMILES:
CCC[C@@H]([C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)Nc1nccs1)N(O)C=O
Target:
MMP

References

Malemud C J . Inhibition of MMPs and ADAM/ADAMTS[J]. Biochemical Pharmacology, 2019. J Yang, Leblanc M E , Cano I , et al. ADAM10 and ADAM17 proteases mediate proinflammatory cytokine-induced and constitutive cleavage of endomucin from the endothelial surface[J]. Journal of Biological Chemistry, 2020.