TargetMol

ML-298

Product Code:
 
TAR-T8966
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8966-1mg1mg£98.00
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TAR-T8966-5mg5mg£135.00
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TAR-T8966-1mL1 mL * 10 mM (in DMSO)£148.00
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TAR-T8966-10mg10mg£173.00
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TAR-T8966-25mg25mg£246.00
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TAR-T8966-50mg50mg£332.00
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TAR-T8966-100mg100mg£461.00
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This product comes from: United States.
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Further Information

Bioactivity:
ML298 is a potent, specific inhibitor of Phospholipase D2 (PLD2, IC50 of 355 nM).
CAS:
1426916-02-0
Formula:
C22H23F3N4O2
Molecular Weight:
432.447
Pathway:
Metabolism
Purity:
0.997
SMILES:
Fc1cccc(c1)N1CNC(=O)C11CCN(CCNC(=O)c2ccc(F)c(F)c2)CC1
Target:
Phospholipase

References

Scott S A , MC O?Reilly, Daniels J S , et al. Development of a Selective, Allosteric PLD2 Inhibitor[M]. PubMed, 2010. Brown K A . Development of dual PLD1/2 and PLD2 selective inhibitors from a common 1,3,8-Triazaspiro[4.5]decane Core: discovery of Ml298 and Ml299 that decrease invasive migration in U87-MG glioblastoma cells.[J]. Journal of Medicinal Chemistry, 2013, 56(6):2695.