TargetMol

VU0155094

Product Code:
 
TAR-T9011
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9011-1mg1mg£166.00
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TAR-T9011-5mg5mg£266.00
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TAR-T9011-1mL1 mL * 10 mM (in DMSO)£294.00
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TAR-T9011-10mg10mg£349.00
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TAR-T9011-25mg25mg£541.00
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TAR-T9011-50mg50mg£744.00
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Quantity:
TAR-T9011-100mg100mg£1,002.00
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TAR-T9011-500mg500mg£1,934.00
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This product comes from: United States.
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Further Information

Bioactivity:
ML397 is a positive allosteric modulator with differential activity at the various group III mGluRs.
CAS:
731006-86-3
Formula:
C24H24N2O4S
Molecular Weight:
436.53
Pathway:
Neuroscience
Purity:
0.98
SMILES:
COC(=O)c1ccc(cc1)-n1c(C)cc(C(=O)CSc2ccc(NC(C)=O)cc2)c1C
Target:
GluR

References

Jalan-Sakrikar N, Field JR, Klar R, Mattmann ME, Gregory KJ, Zamorano R, Engers DW, Bollinger SR, Weaver CD, Days EL, Lewis LM, Utley TJ, Hurtado M, Rigault D, Acher F, Walker AG, Melancon BJ, Wood MR, Lindsley CW, Conn PJ, Xiang Z, Hopkins CR, Niswender CM. Identification of positive allosteric modulators VU0155094 (ML397) and VU0422288 (ML396) reveals new insights into the biology of metabotropic glutamate receptor 7. ACS Chem Neurosci. 2014 Dec 17;5(12):1221-37. doi: 10.1021/cn500153z. Epub 2014 Oct 9. PubMed PMID: 25225882; PubMed Central PMCID: PMC4306484.