TargetMol

GW406108X

Product Code:
 
TAR-T9207
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9207-1mg1mg£165.00
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TAR-T9207-5mg5mg£270.00
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TAR-T9207-1mL1 mL * 10 mM (in DMSO)£291.00
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TAR-T9207-10mg10mg£404.00
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TAR-T9207-25mg25mg£704.00
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TAR-T9207-50mg50mg£1,099.00
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TAR-T9207-100mg100mg£1,629.00
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TAR-T9207-200mg200mg£2,448.00
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Further Information

Bioactivity:
GW108X is a Kif15 inhibitor with an IC50 of 0.82 uM in ATPase assays. GW837331X is also an ULK1 kinase inhibitor with pIC50 values of 6.37 (427 nM) and block autophagic flux.
CAS:
1644443-92-4
Formula:
C20H11Cl2NO4
Molecular Weight:
400.21
Pathway:
Cytoskeletal Signaling; Autophagy
Purity:
0.98
SMILES:
Oc(c(Cl)cc(/C=C(/c(cc(cc1)C(c2ccco2)=O)c1N1)C1=O)c1)c1Cl
Target:
Kinesin; Autophagy

References

Zachari M , Rainard J M , Pandarakalam G C , et al. The Identification and characterisation of autophagy inhibitors from the published kinase inhibitor sets[J]. Biochemical Journal, 2020, 477(4).