TargetMol

Thalidomide-PEG4-Propargyl

Product Code:
 
TAR-T9389
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T9389-1mg1mg£114.00
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TAR-T9389-5mg5mg£159.00
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TAR-T9389-10mg10mg£197.00
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TAR-T9389-25mg25mg£277.00
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Quantity:
TAR-T9389-50mg50mg£374.00
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Quantity:
TAR-T9389-100mg100mg£523.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Thalidomide-PEG4-Propargyl is a synthetic E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker which can be used in PROTAC technology[1].
CAS:
2098799-77-8
Formula:
C24H28N2O9
Molecular Weight:
488.49
Pathway:
PROTAC
Purity:
0.9746
SMILES:
C#CCOCCOCCOCCOCCOc1cccc(C(N2C(CCC(N3)=O)C3=O)=O)c1C2=O
Target:
E3 Ligase Ligand-Linker Conjugate

References

Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine. Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11.