TargetMol

iMDK

Product Code:
 
TAR-T9460
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9460-1mg1mg£114.00
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TAR-T9460-5mg5mg£173.00
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TAR-T9460-1mL1 mL * 10 mM (in DMSO)£220.00
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TAR-T9460-10mg10mg£229.00
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TAR-T9460-25mg25mg£436.00
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TAR-T9460-50mg50mg£610.00
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Quantity:
TAR-T9460-100mg100mg£838.00
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Quantity:
TAR-T9460-500mg500mg£1,613.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
iMDK quarterhydrate is a potent PI3K inhibitor that inhibits the growth factor MDK (also known as midkine or MK). iMDK quarterhydrate synergistically inhibits non-small cell lung cancer (NSCLC) with MEK inhibitors without harming normal cells and mice.
CAS:
881970-80-5
Formula:
C21H13FN2O2S
Molecular Weight:
376.41
Pathway:
PI3K/Akt/mTOR signaling
Purity:
0.9977
SMILES:
Fc1ccc(Cc2cn3cc(nc3s2)-c2cc3ccccc3oc2=O)cc1
Target:
PI3K

References

Naomasa Ishida, et al. A novel PI3K inhibitor iMDK suppresses non-small cell lung Cancer cooperatively with A MEK inhibitor. Exp Cell Res. 2015 Jul 15;335(2):197-206.