TargetMol

Binodenoson

Product Code:
 
TAR-T9516
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9516-1mg1mg£182.00
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TAR-T9516-5mg5mg£309.00
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TAR-T9516-1mL1 mL * 10 mM (in DMSO)£333.00
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TAR-T9516-10mg10mg£430.00
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TAR-T9516-25mg25mg£664.00
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TAR-T9516-50mg50mg£863.00
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Quantity:
TAR-T9516-100mg100mg£1,187.00
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Further Information

Bioactivity:
Binodenoson is a potent and selective A2A adenosine receptor agonist (KD=270 nM). Binodenoson is being developed as a short-acting coronary vasodilator as an adjunct to radiotracers for use in myocardial stress imaging[1].
CAS:
144348-08-3
Formula:
C17H25N7O4
Molecular Weight:
391.432
Pathway:
GPCR/G Protein; Neuroscience
Purity:
0.9984
SMILES:
Nc1nc(NN=CC2CCCCC2)nc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Target:
Adenosine Receptor

References

Sullivan GW, et al. Neutrophil A2A adenosine receptor inhibits inflammation in a rat model of meningitis: synergy with the type IV phosphodiesterase inhibitor, rolipram. J Infect Dis. 1999;180(5):1550-1560. Glover DK, et al. Pharmacological stress thallium scintigraphy with 2-cyclohexylmethylidenehydrazinoadenosine (WRC-0470). A novel, short-acting adenosine A2A receptor agonist. Circulation. 1996;94(7):1726-1732.