TargetMol

Compound 1T-0219 (SC)

Product Code:
 
TAR-T9545
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T9545-1mg1mg£189.00
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TAR-T9545-5mg5mg£340.00
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TAR-T9545-10mg10mg£470.00
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TAR-T9545-25mg25mg£707.00
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TAR-T9545-50mg50mg£978.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Compound 1T-0219 (SC) is a blocker of AKT1-FAK interaction reducing the stimulation of FAK phosphorylation in response to extracellular pressure in human SW620 colon cancer cells without affecting basal FAK phosphorylation.
CAS:
383147-92-0
Formula:
C20H19N3O7
Molecular Weight:
413.386
Pathway:
Cytoskeletal Signaling; Angiogenesis; Tyrosine Kinase/Adaptors
Purity:
0.98
SMILES:
COc1ccc(cc1)C(=O)ON=C1/CCCCC1c1ccc(cc1[N+]([O-])=O)[N+]([O-])=O
Target:
FAK

References

More SK, Vomhof-Dekrey EE, Basson MD. ZINC4085554 inhibits cancer cell adhesion by interfering with the interaction of Akt1 and FAK. Oncol Lett. 2019 Jun;17(6):5251-5260. doi: 10.3892/ol.2019.10192. Epub 2019 Mar 27. PMID: 31186741; PMCID: PMC6507311.