TargetMol

JI130

Product Code:
 
TAR-T9588
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9588-1mg1mg£196.00
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TAR-T9588-5mg5mg£325.00
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TAR-T9588-1mL1 mL * 10 mM (in DMSO)£357.00
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TAR-T9588-10mg10mg£478.00
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TAR-T9588-25mg25mg£733.00
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TAR-T9588-50mg50mg£978.00
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TAR-T9588-100mg100mg£1,299.00
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TAR-T9588-500mg500mg£2,456.00
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Further Information

Bioactivity:
JI130 is able to impair the ability of Hes1 to repress transcription. JI130 treatment significantly reduced tumor volume in a murine pancreatic tumor xenograft model.
CAS:
2234271-86-2
Formula:
C23H24N2O3
Molecular Weight:
376.45
Purity:
0.98
SMILES:
COc1cccc2c1[nH]cc2/C=C/C(NCCc(cccc1)c1OCC=C)=O

References

Perron A, et al. Small-molecule screening yields a compound that inhibits the cancer-associated transcription factor Hes1 via the PHB2 chaperone. J Biol Chem. 2018 May 25;293(21):8285-8294.