TargetMol

ASK1-IN-1

Product Code:
 
TAR-T9697
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9697-1mg1mg£149.00
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TAR-T9697-5mg5mg£252.00
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TAR-T9697-1mL1 mL * 10 mM (in DMSO)£270.00
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TAR-T9697-10mg10mg£389.00
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TAR-T9697-25mg25mg£621.00
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TAR-T9697-50mg50mg£854.00
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Quantity:
TAR-T9697-100mg100mg£1,131.00
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This product comes from: United States.
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Further Information

Bioactivity:
ASK1-IN-1 is an inhibitor of apoptosis signal-regulating kinase 1 which is a key mediator in the apoptotic and inflammatory cellular stress response with an IC50 of 21 nM in biochemica assays.
CAS:
2411382-24-4
Formula:
C19H19N9O2
Molecular Weight:
405.41
Pathway:
Apoptosis
Purity:
0.98
SMILES:
CC(C)n1c(-c2cccc(NC(c3cn(-c4nccnc4)nc3OC)=O)n2)nnc1
Target:
ASK

References

Xin Z, et al. Discovery of CNS-Penetrant Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitors. ACS Med Chem Lett. 2020;11(4):485-490. Published 2020 Feb 12.