TargetMol

BTK inhibitor 17

Product Code:
 
TAR-T9706
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9706-1mg1mg£211.00
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TAR-T9706-5mg5mg£369.00
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TAR-T9706-1mL1 mL * 10 mM (in DMSO)£370.00
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TAR-T9706-10mg10mg£517.00
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TAR-T9706-25mg25mg£790.00
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TAR-T9706-50mg50mg£1,050.00
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Quantity:
TAR-T9706-100mg100mg£1,396.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
BTK inhibitor 17 is a potent irreversible BTK inhibitor (IC50 = 2.1 nM). BTK inhibitor 17 can be used in rheumatoid arthritis studies.
CAS:
1858206-76-4
Formula:
C25H24N6O3
Molecular Weight:
456.5
Pathway:
Angiogenesis; Tyrosine Kinase/Adaptors
Purity:
0.9957
SMILES:
C=CC(N(CCC1)C[C@@H]1n(c1c2C(N)=NNC1=O)nc2-c(cc1)ccc1Oc1ccccc1)=O
Target:
BTK

References

Xuejun Zhang, et al. Discovery and Evaluation of Pyrazolo[3,4- d]pyridazinone as a Potent and Orally Active Irreversible BTK Inhibitor. ACS Med Chem Lett. 2019 Dec 11;11(10):1863-1868.