TargetMol

LEI110

Product Code:
 
TAR-T9753
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9753-1mg1mg£148.00
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Quantity:
TAR-T9753-1mL1 mL * 10 mM (in DMSO)£242.00
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TAR-T9753-5mg5mg£242.00
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TAR-T9753-10mg10mg£322.00
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Quantity:
TAR-T9753-25mg25mg£499.00
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Quantity:
TAR-T9753-50mg50mg£687.00
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Quantity:
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Further Information

Bioactivity:
LEI110 is a potent Phospholipase A2, group XVI (PLA2G16) inhibitor with an Ki value of 20 nM. LEI110 is a selective pan-inhibitor of the HRASLS family of thiol hydrolases (i.e., PLA2G16, HRASLS2, RARRES3 and iNAT).
CAS:
2313525-90-3
Formula:
C25H23F3N2O3
Molecular Weight:
456.46
Pathway:
Metabolism
Purity:
0.98
SMILES:
O=C(CCCc1ccccc1)C(NCCc(cc1)ccc1Oc1ncc(C(F)(F)F)cc1)=O
Target:
Phospholipase

References

Zhou J, et al. Activity-Based Protein Profiling Identifies ?-Ketoamides as Inhibitors for Phospholipase A2 Group XVI. ACS Chem Biol. 2019 Feb 15;14(2):164-169.