TargetMol

MRTX0902

Product Code:
 
TAR-T9755
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9755-1mg1mg£140.00
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Quantity:
TAR-T9755-5mg5mg£242.00
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TAR-T9755-10mg10mg£322.00
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TAR-T9755-25mg25mg£603.00
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TAR-T9755-50mg50mg£922.00
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Quantity:
TAR-T9755-100mg100mg£1,460.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
MRTX0902 is an effective and high selective inhibitor of SOS1 with an IC50 of 46 nM and a Ki of 2 nM.
CAS:
2654743-22-1
Formula:
C22H24N6O
Molecular Weight:
388.47
Pathway:
MAPK
Purity:
0.98
SMILES:
N([C@H](C)C1=C(C)C(C#N)=CC=C1)C=2C3=C(C=NC(=C3)N4CCOCC4)C(C)=NN2
Target:
Raf

References

Ketcham JM, et al. Design and Discovery of MRTX0902, a Potent, Selective, Brain-Penetrant, and Orally Bioavailable Inhibitor of the SOS1:KRAS Protein-Protein Interaction. J Med Chem. 2022 Jul 28;65(14):9678-9690.