TargetMol

5-(3-bromo-4,5-dihydroisoxazol-5-yl)-3-(4-(tert-butyl)phenyl)-1,2,4-oxadiazole

Product Code:
 
TAR-T9858
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9858-1mg1mg£227.00
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TAR-T9858-5mg5mg£422.00
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TAR-T9858-1mL1 mL * 10 mM (in DMSO)£438.00
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TAR-T9858-10mg10mg£589.00
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TAR-T9858-25mg25mg£863.00
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TAR-T9858-50mg50mg£1,179.00
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TAR-T9858-100mg100mg£1,564.00
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TAR-T9858-500mg500mg£3,058.00
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Further Information

Bioactivity:
5-(3-bromo-4,5-dihydroisoxazol-5-yl)-3-(4-(tert-butyl)phenyl)-1,2,4-oxadiazole is a 3-Br-isoxazoline-Based Inhibitors against Plasmodium falciparum (D10 and W2 strains) and Leishmania spp. (L. infantum and L. tropica) Promastigotes with IC50s of 0.035, 0.058, 3.5 and 7.5 μM.
CAS:
0
Formula:
C15H16BrN3O2
Molecular Weight:
350.21
Pathway:
Microbiology/Virology
Purity:
0.98
SMILES:
CC(C1=CC=C(C2=NOC(C3CC(Br)=NO3)=N2)C=C1)(C)C
Target:
Parasite

References

Galbiati A, et al. Development of Potent 3-Br-isoxazoline-Based Antimalarial and Antileishmanial Compounds. ACS Med Chem Lett. 2021 Oct 13;12(11):1726-1732.