TargetMol

GPR183

Product Code:
 
TAR-T9975
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9975-1mg1mg£148.00
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TAR-T9975-5mg5mg£269.00
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TAR-T9975-1mL1 mL * 10 mM (in DMSO)£289.00
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TAR-T9975-10mg10mg£389.00
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TAR-T9975-25mg25mg£603.00
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TAR-T9975-50mg50mg£830.00
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TAR-T9975-100mg100mg£1,099.00
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Further Information

Bioactivity:
GPR183 is a chemotactic receptor known for its role in the maturation of B cells, and the endogenous ligand is the oxysterol 7α,25-dihydroxycholesterol (7α,25-OHC). GPR183 can be used in research on inflammatory bowel disease (IBD).
CAS:
1241280-25-0
Formula:
C19H19F3N2O2
Molecular Weight:
364.368
Purity:
0.98
SMILES:
Fc1cc(NC(=O)CCc2ccc(F)c(F)c2)cc(c1)N1CCOCC1

References

Misselwitz B, et al. The oxysterol receptor GPR183 in inflammatory bowel diseases. Br J Pharmacol. 2021 Aug;178(16):3140-3156. Braden K, et al. GPR183-Oxysterol Axis in Spinal Cord Contributes to Neuropathic Pain. J Pharmacol Exp Ther. 2020 Nov;375(2):367-375.