TargetMol

Desoxyrhaponticin

Product Code:
 
TAR-TJS0387
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TJS0387-1mg1mg£106.00
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TAR-TJS0387-1mL1 mL * 10 mM (in DMSO)£148.00
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TAR-TJS0387-5mg5mg£148.00
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TAR-TJS0387-10mg10mg£203.00
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TAR-TJS0387-25mg25mg£338.00
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TAR-TJS0387-50mg50mg£470.00
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TAR-TJS0387-100mg100mg£630.00
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Further Information

Bioactivity:
1. Desoxyrhaponticin is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this compound can be explained, in part at least, by inhibition of glucose transport in the small intestine and inhibition of glucose reabsorption in the kidney. 2. Desoxyrhaponticin and rhaponticin could be considered as promising fatty acid synthase(FAS) inhibitors, they could inhibit intracellular FAS activity and downregulate FAS expression in human breast cancer MCF-7 cells.
CAS:
30197-14-9
Formula:
C21H24O8
Molecular Weight:
404.415
Pathway:
Metabolism; Apoptosis
Purity:
0.98
SMILES:
COc1ccc(C=Cc2cc(O)cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c2)cc1
Target:
Apoptosis; Fatty Acid Synthase

References

Li P , Tian W , Wang X , et al. Inhibitory effect of desoxyrhaponticin and rhaponticin, two natural stilbene glycosides from the Tibetan medicinal plant Rheum tanguticum Maxim. ex Balf, on fatty acid synthase and human breast cancer cells[J]. Food & Function, 2014, 5(2):251-256.