TargetMol

Qingyangshengenin B

Product Code:
 
TAR-TMS1461
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TMS1461-1mg1mg£138.00
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TAR-TMS1461-5mg5mg£228.00
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TAR-TMS1461-10mg10mg£307.00
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TAR-TMS1461-25mg25mg£470.00
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TAR-TMS1461-50mg50mg£651.00
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TAR-TMS1461-100mg100mg£863.00
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Further Information

Bioactivity:
Qingyangshengenin B is a C-21 steroidal glycoside isolated from Qingyangshen. Qingyangshengenin B protects against Aβ toxicity, which decreases Aβ deposition by decreasing the expression of Aβ at the mRNA level. Qingyangshengenin B has antiepileptic and anti-aging effects, it can extend lifespan, increase heat stress-resistance, delay body paralysis, and increase the chemotaxis response in C. elegans models of Alzheimer's disease. Otophylloside B can suppress the seizure-like locomotor activity caused by pentylenetetrazole in zebrafish.
CAS:
106758-54-7
Formula:
C49H78O16
Molecular Weight:
923.147
Pathway:
Neuroscience
Purity:
0.9926
SMILES:
[H][C@@]1(C[C@H](OC)[C@H](O[C@@]2([H])C[C@H](OC)[C@H](O[C@@]3([H])C[C@@H](OC)[C@H](O)[C@@H](C)O3)[C@@H](C)O2)[C@@H](C)O1)O[C@H]1CC[C@@]2(C)C(C1)=CC[C@]1(O)[C@]2([H])C[C@@H](OC(=O)C=C(/C)C(C)C)[C@]2(C)[C@@](O)(CC[C@]12O)C(C)=O
Target:
Beta Amyloid

References

Yang, Jie, Wan, et al. The Lifespan-Promoting Effect of Otophylloside B in Caenorhabditis elegans[J]. Natural Products and Bioprospecting, 2015, 5(4):177-183.