TargetMol

Onjisaponin B

Product Code:
 
TAR-TN1140
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-TN1140-1mg1mg£135.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-TN1140-5mg5mg£223.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-TN1140-10mg10mg£294.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-TN1140-1mL1 mL * 10 mM (in DMSO)£406.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-TN1140-25mg25mg£447.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-TN1140-50mg50mg£624.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-TN1140-100mg100mg£860.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
Onjisaponin B induces autophagy via the AMPK-mTOR signaling pathway, increases the NGF level and accelerates both the removal of mutant huntingtin and A53T α?-synuclein, it may have potential therapeutic effects on Parkinson disease, Alzheimer disease and Huntington disease.
CAS:
35906-36-6
Formula:
C75H112O35
Molecular Weight:
1573.686
Pathway:
Autophagy; PI3K/Akt/mTOR signaling; Chromatin/Epigenetic
Purity:
0.992
SMILES:
COc1ccc(C=CC(=O)O[C@@H]2[C@H](C)O[C@H](OC(=O)[C@@]34CCC(C)(C)C[C@@H]3C3=CC[C@@H]5[C@]6(C)C[C@H](O)[C@H](O[C@H]7O[C@H](CO)[C@@H](O)[C@@H](O)[C@H]7O)[C@](C)([C@@H]6CC[C@@]5(C)C3(CO)CC4)C(O)=O)[C@@H](O[C@H]3O[C@H](C)[C@@H](O[C@H]4OC[C@@H](O[C@H]5O[C@H](CO)[C@@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H]4O)[C@@H](O)[C@H]3O)[C@@H]2O[C@H]2O[C@H](C)[C@H](O)[C@H](O)[C@@H]2O)cc1
Target:
AMPK; mTOR; Autophagy

References

Onjisaponin B derived from Radix Polygalae enhances autophagy and accelerates the degradation of mutant ??-synuclein and huntingtin in PC-12 cells.Int J Mol Sci. 2013 Nov 15;14(11):22618-41.