TargetMol

3-O-Methylquercetin

Product Code:
 
TAR-TN1266
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN1266-50mg50mgEnquire
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TAR-TN1266-1mg1mg£142.00
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TAR-TN1266-5mg5mg£230.00
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TAR-TN1266-10mg10mg£309.00
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Further Information

Bioactivity:
3-O-Methylquercetin is a selective and competitive PDE3/PDE4 inhibitor, and inhibits PDE3 than PDE4 with a low Km value. 3-O-Methylquercetin inhibits total cAMP- and cGMP-phosphodiesterase (PDE) of guinea pig trachealis at low concentrations.
CAS:
1486-70-0
Formula:
C16H12O7
Molecular Weight:
316.265
Pathway:
GPCR/G Protein; Metabolism; Immunology/Inflammation
Purity:
0.998
SMILES:
COc1c(oc2cc(O)cc(O)c2c1=O)-c1ccc(O)c(O)c1
Target:
IL Receptor; cAMP; PDE

References

Fasolo D, Bassani VL, Teixeira HF. Development of topical nanoemulsions containing quercetin and 3-O-methylquercetin. Pharmazie. 2009 Nov;64(11):726-30. Wun-Chang Ko, et al. 3-O-methylquercetin More Selectively Inhibits Phosphodiesterase Subtype 3. Planta Med. 2003 Apr;69(4):310-5.