TargetMol

7Beta-Hydroxycholesterol

Product Code:
 
TAR-TN1338
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-TN1338-100mg100mgEnquire
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TAR-TN1338-50mg50mgEnquire
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Further Information

Bioactivity:
7beta-Hydroxycholesterol, a major cytotoxin in oxidized LDL, induces Ca(2+) oscillations, MAP kinase activation and apoptosis in human aortic smooth muscle cells.
CAS:
566-27-8
Formula:
C27H46O2
Molecular Weight:
402.663
Pathway:
MAPK; Metabolism; Membrane transporter/Ion channel
Purity:
0.98
SMILES:
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3[C@@H](O)C=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
Target:
LDL; Calcium Channel; MAPK

References

Cytotoxic effect of 7beta-hydroxycholesterol on human NCI-H460 lung cancer cells.Biol. Pharm. Bull., 2005, 28(8):1377-80.