TargetMol

Cleomiscosin A

Product Code:
 
TAR-TN1511
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN1511-1mg1mg£142.00
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TAR-TN1511-5mg5mg£242.00
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TAR-TN1511-1mL1 mL * 10 mM (in DMSO)£254.00
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TAR-TN1511-10mg10mg£332.00
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TAR-TN1511-25mg25mg£540.00
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TAR-TN1511-50mg50mg£742.00
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TAR-TN1511-100mg100mg£978.00
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Further Information

Bioactivity:
Cleomiscosin A is derived from Acer okamotoanum leaf and twig and shows inhibitory activity to TNF-α secretion of the mouse peritoneal macrophages. Cleomiscosin A can be used in studies about the prevention of LDL oxidation in atherosclerotic lesions.
CAS:
76948-72-6
Formula:
C20H18O8
Molecular Weight:
386.356
Pathway:
oxidation-reduction; Apoptosis; Metabolism
Purity:
1
SMILES:
COc1cc(ccc1O)[C@H]1Oc2c(OC)cc3ccc(=O)oc3c2O[C@@H]1CO
Target:
LDL; Antioxidant; TNF

References

Jin W, et al. Antioxidant activity of cleomiscosins A and C isolated from Acer okamotoanum. Arch Pharm Res. 2007 Mar;30(3):275-81. Ma M, et al. [Chemical constituents from branch of Macaranga adenantha and their TNF-alpha inhibitory activity]. Zhongguo Zhong Yao Za Zhi. 2007 Jun;32(12):1175-9. Chinese. Sharma S, et al. Synthesis and anti-inflammatory activity of derivatives of coumarino-lignoid, cleomiscosin A and its methyl ether. Eur J Med Chem. 2010;45(11):5150-5156.