TargetMol

Dihydrocucurbitacin B

Product Code:
 
TAR-TN1579
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN1579-1mg1mg£201.00
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TAR-TN1579-2mg2mg£266.00
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TAR-TN1579-5mg5mg£402.00
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TAR-TN1579-10mg10mg£544.00
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TAR-TN1579-25mg25mg£828.00
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TAR-TN1579-50mg50mg£1,091.00
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Further Information

Bioactivity:
Dihydrocucurbitacin B is isolated from the roots of Cayaponia tayuya with anti-cancer activity.
CAS:
13201-14-4
Formula:
C32H48O8
Molecular Weight:
560.728
Pathway:
Apoptosis; Neuroscience; Immunology/Inflammation
Purity:
0.98
SMILES:
[H][C@@]12C[C@H](O)C(=O)C(C)(C)C1=CC[C@@]1([H])[C@]3(C)C[C@@H](O)[C@H]([C@@](C)(O)C(=O)CCC(C)(C)OC(C)=O)[C@@]3(C)CC(=O)[C@@]21C
Target:
IL Receptor; TNF; COX

References

Escandell JM, et al. Dihydrocucurbitacin B inhibits delayed type hypersensitivity reactions by suppressing lymphocyte proliferation. J Pharmacol Exp Ther. 2007 Sep;322(3):1261-8. Lang KL, et al. Synthesis and cytotoxic activity evaluation of dihydrocucurbitacin B and cucurbitacin B derivatives. Bioorg Med Chem. 2012 May 1;20(9):3016-30.