TargetMol

Ganoderic acid H

Product Code:
 
TAR-TN1664
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-TN1664-1mg1mg£299.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-TN1664-5mg5mg£758.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
Ganoderic acid H is a potent antitumour agent, it mediates its biological effects through the inhibition of transcription factors AP-1 and NF-κB, resulting in the suppression of secretion of uPA.
CAS:
98665-19-1
Formula:
C32H44O9
Molecular Weight:
572.695
Pathway:
DNA Damage/DNA Repair; Cell Cycle/Checkpoint; NF-κb
Purity:
0.9714
SMILES:
[H][C@@]12CC(=O)C3=C(C(=O)[C@@H](OC(C)=O)[C@]4(C)[C@H](CC(=O)[C@@]34C)[C@H](C)CC(=O)CC(C)C(O)=O)[C@@]1(C)CC[C@H](O)C2(C)C
Target:
NF-κB; DNA/RNA Synthesis; CDK

References

Jiang J, Grieb B, Thyagarajan A, Sliva D. Ganoderic acids suppress growth and invasive behavior of breast cancer cells by modulating AP-1 and NF-kappaB signaling. Int J Mol Med. 2008 May;21(5):577-84.